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Paper Details


Title
Phytochemical investigation, evaluation of antioxidant and cytotoxic activity of the methanol extract of cuscuta reflexa (Stem)
Abstract
Cuscuta reflexais used for treating constipation, flatulence, body pains, itchy skin, frequent urination, dry eyes, ringing in the ears, lower back pain, blurred vision, tired eyes, hair growth promoters ability to prevent certain cancer cells and thus reduce the incidence of cancer. Its can build protection from cerebral ischemia, advance heart blood, tonify kidney. The present study was carried out to investigate phytochemical, antioxidant and cytotoxic activity of stem of Cuscuta reflexamethanolic extracts. The cytotoxic activity was determined by using brine shirmp lethality bioassay. For cytotoxic activity, extracts showed LC 50 183.64 μg/ml. On the other hand, the reference standard Vincristine sulphate showed LC 50 value was 7.27 μg/ml. It is also revealed thatthe extract of Cuscuta reflexapossess antioxidant activity IC50 157.80μg/mlcompare to standard IC50 64.38 μg/ml.The potential of these activities may be due to the presence of most of the phytochemicals which supports previous claims and validate its uses as an expected folk medicine.
Keywords
Cuscuta reflexa, Vincristine Sulphate, DPPH, Antioxidant
Authors
Md. Mamunur Rashid Munna, A.K. Azad; Fahadul Islam;Md Faruk Ahmed, Anwar Parvez,Md. Mizanur Rahman, Md. Sarowar Hossain.
Phone
Journal or Conference Name
PharmacologyOnline
Publish Year
2019
Indexing
Scopus