Proton Induced Gamma Emission Technique (PIGE) was employed for the determination of trace elemental concentrations in some local chewing stick plants of pharmacological importance. The familiar local name of chewing stick plants studied are Nishinda, Neem, Bely-asra, Bhat, Joytun, Kaminee, Akondo, Khejur, Bohera, Moth-bhringraj, Batul, Olut-kumbal, Sheora and Motkila. Proton beam from the 3 MeV Van de Graaff Accelerator at the AECD was used for irradiating the samples. Proton beam energy was 2.5 MeV and the beam current was 20 nA. As F has important dental carries inhibiting properties, the measurement of its concentration in the common chewing plants is of special interest. The PIGE reaction 19F (p,p’ y) 19F was used for the determination of the concentrations. The certified values of concentrations in NBS SRM 1515 Apple leaves, NBS SRM 1573, Tomato leaves, NBS SRM 1573, Spinach and sediment standard AGV -1 were used as standard for the measurement of concentrations of 23Na, 24Mg, and 25Mg. The natural abundances of Mg are: 24Mg-78.99%, 25Mg-l 0%, and 26Mg-II.O 1%. Using the natural isotopic abundance, the concentrations of Mg isotopes have been calculated. The concentration of 19F was calculated using the calibration curve of cellulose for 197 KeY energy peak. Both leaves and trunks of the chewing stick plants were analyzed. It has been observed that among all the leaf samples investigated, leaves of Neem, a common chewing stick plant, contain the highest amount ofF, which is about 222 ppm. And among all the trunk samples, the highest amount ofF has been observed in Bely-asra plant, which is about 122 ppm. Finally, the significance of the measured results are discussed in the light of their impact on the health care.