The current study was carried out to explore the analgesic, anti-inflammatory and anti-diabetic
potential of methanol extract of Phyllanthus beilei H. The analgesic activities were determined by acetic
acid induced writhing test in mice. The oral administration of doses 500 mg/kg of methanol extract of
Phyllanthus beilei H. inhibited 42.22% of writhing movements compared to standard drug diclofenac-Na
94.28% writhing movement inhibition induced by acetic acid. Anti-inflammatory effect of ethyl acetate
extract was determined after oral administration of 1% Carrageenan, paw edema in mice. Mice treated
with ethyl acetate extract of Phyllanthus beilei H. (500 mg/kg) moderately decreased in paw volume at
180 min and 240 min compared with mice of control group. Here, pronounced effects were observed in
extract group 34.36% inhibition of paw edema compared to that of Standard Group 55.13% inhibition of
paw edema. In the Oral glucose tolerance test the control group of mice exhibited higher blood
glucose levels whereas, mice treated with extract (500 mg/kg) showed significant decrease in blood
glucose level after 30 mins and 120 mins compared with control group of mice.