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Paper Details


Title
Natural bioactive molecules: An alternative approach to the treatment and control of covid-19
Author
Fahadul Islam, ATKIA FARZANA KHAN MEEM, Md Mizanur Rahman, Md. Mohaimenul Islam, Md. Mominur Rahman, Md. Saidur Rahaman, Sristy Bepary,
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Abstract

Several coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to prevent more loss of human lives. Positive-sense RNA viruses with group spikes protruding from their surfaces and an abnormally large RNA genome enclose CoVs. CoVs have already been related to a range of respiratory infectious diseases possibly fatal to humans, such as MERS, SARS, and the current COVID-19 outbreak. As a result, effective prevention, treatment, and medications against human coronavirus (HCoV) is urgently needed. In recent years, many natural substances have been discovered with a variety of biological significance, including antiviral properties. Throughout this work, we reviewed a wide range of natural substances that interrupt the life cycles for MERS and SARS, as well as their potential application in the treatment of COVID-19.

Keywords
COVID-19; SARS-CoV-2; alkaloids; bioactive molecules; coronavirus; flavonoids; terpenoids
Journal or Conference Name
International Journal of Molecular Sciences
Publication Year
2021
Indexing
scopus