Xanthosoma Sagittifolium is a common herb consumed in Bangladesh for its nutritional and traditional medicinal values. The current study was carried out to evaluate the presence of phytochemicals and to screen out antioxidant and antibacterial potentialities of Xanthosoma Sagittifolium (L.) ethanolic leaf extract. Phytochemical screening of extract ensured the presence of carbohydrates, tannins, flavonoids, steroids and alkaloids. Antioxidant activity was evaluated using DPPH free radical scavenging assay where ascorbic acid used as standard. The leaf extract showed free radical scavenging capacity which is an indication that this extract may have antioxidant ingredient. Antimicrobial sensitivity of ethanolic extract was measured by disk diffusion method with MuellerHinton agar media using kanamycin as standard. The extract showed mild activity against four of the tested bacterial species such as Bacillus subtilis, Staphylococcus aureus. Escherichia coli, Salmonella enterica, Vibrio cholera and Shigella dysenteriae