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In vitro anthelmintic activity ethanolic leaves extract of gynura procumbens, a prospective medicinal plant
Anthelmictic activity of crude gynura procumbens leaves extract was evaluated using adult earthwarms.Gynura procumbens(Lour.) Merr. (Family Asteraceae) is a medicinal plants often found in tropical Asian countries such as China, Thailand, Indonesia, Malaysia, Vietnam. Traditionally, it is widely used in a wide variety of countries to treat a wide variety of health disorders such as kidney discomfort, rheumatism, diabetes mellitus, constipation and hypertension. On the basis of traditional uses of G. procumbens plant’s leaves, it seems to possess high therapeutic effect for treatment of various diseases making it a target for pharmacological studies aiming to validate and provide scientific evidence for the traditional claims of its efficacy. For anthelmintic activity standard albandazole preparation 15mg/ml showed paralysis time 11.8 and death time 20.6. The extract of G. Procumbens 25mg/ml (paralysis time 36.4 and death time 52.4), 50mg/ml(paralysis time 22 and death time 41) and 100mg/ml (paralysis time 16 and death time 26). The results of present study specify that the ethanolic extract significantly indicate paralysis and also caused death of worms in dose dependent manner.
Anthelmictic activity, Gynura procumbens, Albandazole,Earthwarms
Shaheen SM, Rashid Harun-Or, Anamul Haque, Ferdous W
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