Microplastic (MP) pollution waste is a global macro problem, and research on MP contamination has been done in marine, freshwater, and terrestrial ecosystems. Preventing MP pollution from hurting them is essential to maintaining coral reefs' ecological and economic benefits. However, the public and scientific communities must pay more attention to MP research on the coral reef regions' distribution, effects, mechanisms, and policy evaluations. Therefore, this review summarizes the global MP distribution and source within the coral reefs. Current knowledge extends the impacts of MP on coral reefs, existing policy, and further recommendations to mitigate MPs contamination on corals are critically analyzed. Furthermore, mechanisms of MP on coral and human health are also highlighted to pinpoint research gaps and potential future studies. Given the escalating plastic usage and the prevalence of coral bleaching globally, there is a pressing need to prioritize research efforts on marine MPs that concentrate on critical coral reef areas. Such investigations should encompass an extensive and crucial understanding of the distribution, destiny, and effects of the MPs on human and coral health and the potential hazards of those MPs from an ecological viewpoint.