Cuscuta reflexa is used for treating constipation, flatulence, body pains, itchy skin, frequent urination, dry eyes, ringing in the ears, lower back pain, blurred vision, tired eyes, hair growth promoters ability to prevent certain cancer cells and thus reduce the incidence of cancer. Its can build protection from cerebral ischemia, advance heart blood, tonify kidney. The present study was carried out to investigate phytochemical, antioxidant and cytotoxic activity of stem of Cuscuta reflexa methanolic extracts. The cytotoxic activity was determined by using brine shirmp lethality bioassay. For cytotoxic activity, ..............