University Based Entrepreneurial Ecosystem is an interconnected tool to develop students’ venture within the university framework. Now-a-days, a udniversity not only plays a vital role in entrepreneurship development, but also develops a systematic process where talented graduates invent, innovate and commercialize their ideas. Encouraging university based entrepreneurial ecosystem can bring a greater change in our societies. Universities are setting institutional arrangement to support the students’ venture. A University based entrepreneurial ecosystem (U-BEE) enables key ecosystem for creating innovative value to commercialize the knowledge which will help to develop enterprising communities. This study combines literature on university based entrepreneurial ecosystem (U-BEE) and shares an entrepreneurship supporting framework applied within a university based framework. This paper indicates that university based entrepreneurial ecosystem (U-BEE) ensures the nurture of the budding businesses to transform into sustainable growth. It requires a stress on working on the innovative ideas, teamwork, appropriate mentoring, networking and strategic relationship development, funding, induction of ideas and effective training and education on venture management, that have to be provided over time. Developing entrepreneurs within the university framework will enhance the industry academy relationship and bring direct impact on new employment generation in the country. This paper recommends a supportive framework to develop, nurture, initiate and implement the idea throughout the university to effect in creating ventures.