This dataset presents demodulated in-phase (I) and quadrature (Q) ultrasound data collected from the human hand and forearm using a Verasonics Vantage 64LE system with an L11–5v linear array transducer. A total of 48 .mat files have been acquired from healthy adult subjects, yielding 4800 data samples. The dataset comprises both single-angle and multi-angle acquisitions, indicated in the filenames, and includes raw IQ data prior to B-mode image formation. Multi-angle files capture sequences with shape (400, 2, 256, 256), representing two channels (I and Q) across multiple insonification angles. Single-angle files provide spatially consistent data for baseline comparison. This dataset supports research in ultrasound signal analysis, beamforming alternatives, and deep learning-based image reconstruction. All data are stored in MATLAB format, are anonymized, and are publicly available through Mendeley Data.