Despite facing economic challenges, Jordan has a competitive position among Arab countries in terms of adopting emerging technologies, which is seen as an opportunity to reduce healthcare costs in a developing country like Jordan. TAM is the study's underlying theory, which has been expanded to include perceived privacy, perceived security, and perceived trust. The current study aims to predict the behavioural intention of Jordanian healthcare professionals to use blockchain-based electronic health record systems. Furthermore, the purpose of this study is to investigate the mechanism by which perceived privacy and perceived security influence healthcare professionals' behavioural intention to use blockchain technology in Jordan. This study proposed perceived usefulness, perceived ease of use, and perceived trust as mediators. The quantitative approach was used to collect data from 389 Jordanian healthcare professionals working in the public sector via cross-sectional surveys. The data was analysed with Smart-PLS and IBM-SPSS. Except for the influence of perceived security on perceived usefulness, all of the supposed relationships were supported in this study. Furthermore, all suggested mediating relationships were supported, with the exception of the mediation role of perceived usefulness between the influence of perceived security on behavioural intention. The study's results could be helpful in developing future policies. Furthermore, the Jordanian healthcare sector could use these findings to develop strategies that encourage the adoption of secure and decentralised digital platforms, such as blockchain technology.