The growing sophistication of deepfake technologies has emerged as acritical threat to the credibility of digital media by generating highly realisticyet fabricated visual content. This erodes public trust, elevates securityvulnerabilities, and challenges information integrity across online platforms.Despite notable advancements, existing research still suffers from limited datadiversity, insufficient model explainability, and inadequate model evaluation.To overcome this limitation, a framework for detecting deepfake videomanipulation by using a transfer learning approach was introduced. Eachextracted frame was processed by a convolutional neural network (CNN)-basedmodel to obtain frame-level predictions, which were subsequently aggregatedto produce the final video-level prediction using a predefined threshold.The publicly available, widely adopted FaceForensics++ dataset was used,which contains high-quality videos generated using advanced manipulationtechniques. Various CNN architectures, including Xception, Densenet121,InceptionResNetV2, ResNet50, and EfficientNetB3, were explored along withrigorous hyperparameter tuning. Among these, the Xception architectureoutperformed others by achieving a test accuracy of 94.5%. Gradient-weightedclass activation mapping (Grad-CAM), generalized gradient-based visualexplanations (Grad-CAM++), and Shapley additive explanations (SHAP) wereemployed to enhance model explainability by visualizing the key regions thatinfluence deepfake detection. The research offers an effective approach toaddress deepfake threats and safeguard information integrity in contemporaryindustry 4.0